Association with Health Conditions
Oxidative stress doesn’t really sound all that bad, but in truth, it’s a killer. It is associated with conditions and illness that include Alzheimer’s disease, heart failure, Parkinson’s illness, myocardial infarction (a cardiovascular disease that prevents obstructs the blood supply to a part of the heart muscle triggering it to pass away) and fatigue syndrome.
Your body and Oxidative Stress
Oxidative stress is associated with an increase of reactive oxidative species. These are better known as oxy-radicals, peroxides and free radicals. Or even as a significant reduction in the capability of the body’s antioxidant defense systems. These antioxidant defenses consist of the natural production and existence of glutathione.
When your body loses the capability to efficiently protect itself- at a cellular level- from free radicals and peroxides by having a sufficient and effective supply of anti-oxidants to neutralize them, the resulting condition is oxidative stress.
Reactive oxidative types have numerous sources – both internally produced and externally presented.
External and Internal Free Radicals
Externally, free radical damage is the outcome of contaminants and pathogens in our bodies. Contamination, cigarette smoke, chemotherapy, radiation, UV damage, stress are also contributors.
Our own immune system creates and releases free radicals to attack targeted intruders and contaminants. Factors like aging interfere with our normal ability to fend off oxidative stress. As the damage builds up, our defenses are further compromised.
Oxidative stress and the damage triggered by free radicals in likewise responsible for damage to our DNA. There is an ongoing process of DNA repair work that takes place in both the nucleus and mitochondria organelles of each cell. Mitochondrial DNA (mtDNA) is typically based on an extremely oxidative environment. Without a sufficient supply of anti-oxidants, the DNA can be either damaged or altered.
How it affects healthy aging
Oxidative stress has actually been strongly linked to aging and according to the Free Radical Theory of Aging. It is the built up particles of damaged cells brought on by the uncontrolled action of free radicals that deteriorates our different organ systems and hastens their death. A fine example of the damage caused to cells and cellular DNA by oxidative damage can be easily discovered in the skin of individuals who have actually been chronically overexposed to UV rays.
The list of signs of free radical damage goes on. However one that many people can relate to is the long-term or continuous discomfort suffered as a result of persistent swelling. Anti-oxidants play a crucial function in the prevention of persistent swelling by decreasing oxidative damage.
Here is another article which explains the effects of oxidative stress on the body.
Or visit this page, which explains free radicals and antioxidants.